Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC146Coiled-coil domain containing 146. (702 aa)    
Predicted Functional Partners:
GMNN
Geminin DNA replication inhibitor.
    
   0.938
RSPH14
Radial spoke head 14 homolog.
   
  
 0.729
LRRC23
Leucine rich repeat containing 23.
   
 
 0.710
CCDC113
Coiled-coil domain containing 113.
  
  
 0.700
CABCOCO1
Ciliary associated calcium binding coiled-coil 1.
      
 0.693
TSNAXIP1
Translin-associated factor X interacting protein 1.
   
 
 0.688
ZSWIM2
Zinc finger SWIM-type containing 2.
    
 
 0.674
CFAP161
Cilia and flagella associated protein 161.
   
  
 0.668
DLEC1
DLEC1 cilia and flagella associated protein.
    
 0.658
LRRC34
Leucine rich repeat containing 34.
      
 0.658
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.