STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3A102_LATCHPH domain-containing protein. (229 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.861
H3AZT3_LATCH
GRB2 related adaptor protein b.
   
 0.670
GRAP2
GRB2 related adaptor protein 2.
   
 0.665
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.627
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.611
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.611
SHC3
SHC adaptor protein 3.
   
 0.570
SHC1
SHC adaptor protein 1.
   
 0.570
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.565
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.565
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.