Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A102_LATCHPH domain-containing protein. (229 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.818
ABLIM2
Actin binding LIM protein family member 2.
      
 0.641
ITSN2
Intersectin 2.
   
 0.622
SLC43A1
Solute carrier family 43 member 1.
     
 0.621
SFXN2
Sidoreflexin.
      
 0.592
C12orf73
Chromosome 12 open reading frame 73.
      
 0.591
H3AZT3_LATCH
GRB2 related adaptor protein b.
   
 0.585
GRAP2
GRB2 related adaptor protein 2.
    
 0.579
SHC3
SHC adaptor protein 3.
    
 0.574
SHC1
SHC adaptor protein 1.
    
 0.574
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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