Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SFXN2Sidoreflexin. (323 aa)    
Predicted Functional Partners:
TREH
Trehalase.
      
 0.740
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
    
   0.717
SFXN4
Sideroflexin 4.
  
 
 
0.662
C12orf73
Chromosome 12 open reading frame 73.
    
 
 0.594
H3A102_LATCH
PH domain-containing protein.
      
 0.592
MTBP
MDM2 binding protein.
      
 0.521
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
   
  
 0.503
RNF14
RBR-type E3 ubiquitin transferase.
      
 0.499
EIF1B
Eukaryotic translation initiation factor 1B.
      
 0.486
RANBP3L
RAN binding protein 3 like.
      
 0.470
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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