Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPHB4EPH receptor B4. (976 aa)    
Predicted Functional Partners:
EFNB2
Ephrin B2; Belongs to the ephrin family.
   
 0.922
EFNB1
Ephrin B1; Belongs to the ephrin family.
   
 0.860
EFNA5
Ephrin A5; Belongs to the ephrin family.
   
 0.812
EFNA2
Ephrin A2; Belongs to the ephrin family.
   
 0.765
EFNA1
Ephrin A1; Belongs to the ephrin family.
   
 0.757
RHBDL2
Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
      
 0.655
SRRT
Serrate, RNA effector molecule.
     
 0.628
GIGYF1
GRB10 interacting GYF protein 1.
   
  
 0.623
EFNA3
Ephrin-A3b; Belongs to the ephrin family.
   
 0.561
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
     
 0.531
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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