STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDO2Indoleamine 2,3-dioxygenase 1. (425 aa)    
Predicted Functional Partners:
TDO2
Tryptophan 2,3-dioxygenase.
   
 
 0.978
KYNU
Kynureninase.
   
 0.972
TPH2
Tryptophan hydroxylase 2.
   
 
 0.959
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
 
 0.950
TPH1
Tryptophan hydroxylase 1.
   
 
 0.936
LOC102357693
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 
 0.932
LOC102362765
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.932
AANAT
Aralkylamine N-acetyltransferase.
     
 0.919
LOC102349352
Amine oxidase.
     
 0.913
MAOB
Amine oxidase.
     
 0.913
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.