Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLPP6Phospholipid phosphatase 6. (279 aa)    
Predicted Functional Partners:
LOC102350035
G protein-coupled receptor 182.
    
 
 0.820
GPR182
G protein-coupled receptor 182; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.820
ADCY8
AC_N domain-containing protein.
      
 0.781
EDRF1
Erythroid differentiation regulatory factor 1.
      
 0.716
SUCO
SUN domain containing ossification factor.
      
 0.709
EEF1AKNMT
EEF1A lysine and N-terminal methyltransferase.
      
 0.639
TM9SF4
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
      
 0.576
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
      
 0.555
CRACR2A
Uncharacterized protein.
      
 0.526
HSP90B1
Heat shock protein 90 beta family member 1.
      
 0.515
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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