Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR45BWD repeat domain 45B. (344 aa)    
Predicted Functional Partners:
ATG2A
Autophagy related 2A.
    
 0.985
ATG2B
Autophagy related 2B.
    
 0.985
ATG16L2
ATG16 autophagy related 16-like 2 (S. cerevisiae).
     
 0.922
RAB40C
RAB40C, member RAS oncogene family.
 
    
 0.636
ATG7
Autophagy related 7.
    
 
 0.627
BECN1
Beclin 1, autophagy related.
    
 
 0.618
WIPI1
WD repeat domain, phosphoinositide interacting 1.
   
 0.499
COASY
Coenzyme A synthase.
      
 0.495
WIPI2
WD repeat domain, phosphoinositide interacting 2.
   
 0.488
TMEM59
Transmembrane protein 59.
      
 0.470
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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