Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BLKTyrosine-protein kinase. (447 aa)    
Predicted Functional Partners:
FGFR4
Fibroblast growth factor receptor.
   
  0.945
FGFR3
Fibroblast growth factor receptor.
   
  0.943
STAT3
Signal transducer and activator of transcription.
    
 0.863
LRRC61
Leucine rich repeat containing 61.
    
 0.845
LYN
Tyrosine-protein kinase.
   
   0.816
CD79A
CD79a molecule, immunoglobulin-associated alpha.
   
 0.815
ZNF831
C2H2-type domain-containing protein.
    
 0.812
H2ZSF9_LATCH
Uncharacterized protein.
    
 0.796
H3B644_LATCH
Uncharacterized protein.
 
  
  0.718
STAT1
Signal transducer and activator of transcription.
    
 0.666
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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