Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCXUncharacterized protein. (389 aa)    
Predicted Functional Partners:
DCLK1
Doublecortin like kinase 1; Belongs to the protein kinase superfamily.
 
 
 
 0.997
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
    
 
 0.912
CAMK4
Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily.
 
  
 
 0.903
LOC102361440
Si:ch73-60h1.1.
 
  
 
 0.897
LOC102352549
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
 
  
 
 0.890
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.866
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.847
PSKH1
Protein serine kinase H1; Belongs to the protein kinase superfamily.
 
  
 
 0.840
PHKG1
Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily.
 
      0.830
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
 
      0.823
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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