Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ERAP2Endoplasmic reticulum aminopeptidase 2. (1464 aa)    
Predicted Functional Partners:
AGT
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.738
RPA2
Replication protein A2.
   
 
 0.730
TPP2
Tripeptidyl peptidase 2.
   
 
 0.698
TAPBP
Uncharacterized protein.
   
 
 0.675
DPP3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.592
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 
 0.592
LOC102360396
Si:dkey-26g8.5; Belongs to the peptidase C1 family.
   
 
 0.571
APP
Amyloid beta precursor protein.
    
 
 0.550
TBC1D31
TBC1 domain family member 31.
   
  
 0.541
LOC102367138
DEAD (Asp-Glu-Ala-Asp) box helicase 61; Belongs to the DEAD box helicase family.
   
 
 0.524
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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