Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A180_LATCHRING-type domain-containing protein. (366 aa)    
Predicted Functional Partners:
H3AXB5_LATCH
Poly [ADP-ribose] polymerase.
   
 0.994
H2ZUR6_LATCH
Poly [ADP-ribose] polymerase.
   
 0.784
PARP14
Poly [ADP-ribose] polymerase.
   
 0.784
H3AL20_LATCH
Poly [ADP-ribose] polymerase.
   
 0.720
NUDCD1
NudC domain containing 1.
    
   0.714
RBM43
NID domain-containing protein.
   
   0.698
H3AJ92_LATCH
Poly [ADP-ribose] polymerase.
   
 0.670
IFIH1
Interferon induced with helicase C domain 1.
   
 0.613
LOC102362977
Family with sequence similarity 162 member A.
   
 0.562
UBE2D2
Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.500
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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