Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WWP1E3 ubiquitin-protein ligase. (922 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
  
 
0.998
UBE2L6
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.982
ARRDC1
Arrestin domain containing 1.
    
 
 0.980
SPART
Spartin.
    
 
 0.969
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.968
SMURF2
E3 ubiquitin-protein ligase.
    
0.968
TXNIP
Thioredoxin interacting protein.
    
 
 0.960
SMAD7
Mothers against decapentaplegic homolog.
    
 0.953
WWP2
E3 ubiquitin-protein ligase.
   
   0.946
NEDD4L
E3 ubiquitin-protein ligase.
    
0.944
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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