Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TPK1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (248 aa)    
Predicted Functional Partners:
THTPA
Thiamine triphosphatase.
     
 0.961
LOC106704948
Uncharacterized protein; Belongs to the adenylate kinase family.
     
 0.935
AK5
Adenylate kinase 5; Belongs to the adenylate kinase family.
     
 0.935
H3BAZ9_LATCH
Adenylate kinase 5, like; Belongs to the adenylate kinase family.
     
 0.925
AK7
Adenylate kinase 7.
     
 0.914
AK4
Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
     
 0.905
H3AKY9_LATCH
Uncharacterized protein.
     
 0.905
AK2
Adenylate kinase 2; Belongs to the adenylate kinase family.
     
 0.905
ACP1
LMWPc domain-containing protein.
    
  0.901
LOC102366786
Alkaline phosphatase.
     
  0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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