Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM214AFamily with sequence similarity 214 member A. (1052 aa)    
Predicted Functional Partners:
LMBRD2
LMBR1 domain containing 2.
      
 0.641
RSL24D1
Ribosomal L24 domain containing 1.
      
 0.634
WDR72
WD repeat domain 72.
      
 0.632
WDR7
WD repeat domain 7.
      
 0.632
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
      
 0.626
AP4E1
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
      
 0.615
ZFAND2B
Zinc finger AN1-type containing 2B.
      
 0.611
MBLAC1
Metallo-beta-lactamase domain containing 1.
      
 0.592
MEX3C
Mex-3 RNA binding family member C.
      
 0.591
MEX3D
Mex-3 RNA binding family member D.
      
 0.591
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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