FAM214A protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FAM214A

Family with sequence similarity 214 member A. (1052 aa)

Predicted Functional Partners:

ZFAND2B

0.558

LMBRD2

0.553

RSL24D1

0.552

PIGO

0.469

MBLAC1

0.434

AP4E1

0.424

WDR72

0.422

WDR7

0.422

MEX3C

0.420

MEX3D

0.420

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP4E1	FAM214A	ENSLACP00000007967	ENSLACP00000003440	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Family with sequence similarity 214 member A.	0.424
AP4E1	LMBRD2	ENSLACP00000007967	ENSLACP00000013922	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	LMBR1 domain containing 2.	0.571
AP4E1	PIGO	ENSLACP00000007967	ENSLACP00000001677	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	Phosphatidylinositol glycan anchor biosynthesis class O.	0.510
FAM214A	AP4E1	ENSLACP00000003440	ENSLACP00000007967	Family with sequence similarity 214 member A.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.424
FAM214A	LMBRD2	ENSLACP00000003440	ENSLACP00000013922	Family with sequence similarity 214 member A.	LMBR1 domain containing 2.	0.553
FAM214A	MBLAC1	ENSLACP00000003440	ENSLACP00000008138	Family with sequence similarity 214 member A.	Metallo-beta-lactamase domain containing 1.	0.434
FAM214A	MEX3C	ENSLACP00000003440	ENSLACP00000008283	Family with sequence similarity 214 member A.	Mex-3 RNA binding family member C.	0.420
FAM214A	MEX3D	ENSLACP00000003440	ENSLACP00000018633	Family with sequence similarity 214 member A.	Mex-3 RNA binding family member D.	0.420
FAM214A	PIGO	ENSLACP00000003440	ENSLACP00000001677	Family with sequence similarity 214 member A.	Phosphatidylinositol glycan anchor biosynthesis class O.	0.469
FAM214A	RSL24D1	ENSLACP00000003440	ENSLACP00000015926	Family with sequence similarity 214 member A.	Ribosomal L24 domain containing 1.	0.552
FAM214A	WDR7	ENSLACP00000003440	ENSLACP00000014497	Family with sequence similarity 214 member A.	WD repeat domain 7.	0.422
FAM214A	WDR72	ENSLACP00000003440	ENSLACP00000006818	Family with sequence similarity 214 member A.	WD repeat domain 72.	0.422
FAM214A	ZFAND2B	ENSLACP00000003440	ENSLACP00000012577	Family with sequence similarity 214 member A.	Zinc finger AN1-type containing 2B.	0.558
LMBRD2	AP4E1	ENSLACP00000013922	ENSLACP00000007967	LMBR1 domain containing 2.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.571
LMBRD2	FAM214A	ENSLACP00000013922	ENSLACP00000003440	LMBR1 domain containing 2.	Family with sequence similarity 214 member A.	0.553
LMBRD2	MEX3C	ENSLACP00000013922	ENSLACP00000008283	LMBR1 domain containing 2.	Mex-3 RNA binding family member C.	0.433
LMBRD2	MEX3D	ENSLACP00000013922	ENSLACP00000018633	LMBR1 domain containing 2.	Mex-3 RNA binding family member D.	0.433
LMBRD2	PIGO	ENSLACP00000013922	ENSLACP00000001677	LMBR1 domain containing 2.	Phosphatidylinositol glycan anchor biosynthesis class O.	0.558
LMBRD2	RSL24D1	ENSLACP00000013922	ENSLACP00000015926	LMBR1 domain containing 2.	Ribosomal L24 domain containing 1.	0.444
MBLAC1	FAM214A	ENSLACP00000008138	ENSLACP00000003440	Metallo-beta-lactamase domain containing 1.	Family with sequence similarity 214 member A.	0.434