Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BFARBifunctional apoptosis regulator. (454 aa)    
Predicted Functional Partners:
PDXDC1
Pyridoxal dependent decarboxylase domain containing 1.
      
 0.789
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain.
      
 0.641
CAAP1
Caspase activity and apoptosis inhibitor 1.
      
 0.609
ZC3H12A
Zinc finger CCCH-type containing 12A.
      
 0.587
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.561
NUDCD1
NudC domain containing 1.
    
 
 0.557
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.551
CIDEB
Cell death inducing DFFA like effector b.
      
 0.532
ZNF638
Zinc finger protein 638.
     
 0.480
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.478
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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