Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1202 aa)    
Predicted Functional Partners:
SCN1B
Sodium voltage-gated channel beta subunit 1.
   
 0.978
SCN4B
Sodium voltage-gated channel beta subunit 4.
    
 0.966
LOC102362951
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.930
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.930
LOC102360076
Protein kinase domain-containing protein.
   
 0.913
H2ZUL4_LATCH
Uncharacterized protein.
  
  
 
0.904
CAMK2G
Protein kinase domain-containing protein.
   
 
 0.900
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.858
SCN3B
Sodium voltage-gated channel beta subunit 3.
   
 0.855
SCN2B
Sodium voltage-gated channel beta subunit 2.
   
 0.771
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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