Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (319 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.986
MICU3
Mitochondrial calcium uptake family member 3.
    
 0.954
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
   0.720
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.697
MCUR1
Mitochondrial calcium uniporter regulator 1.
    
 
 0.650
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
     
 0.601
H3A9W0_LATCH
AAA domain-containing protein.
     
 0.601
PHB2
Prohibitin.
     
 0.599
LOC102349562
Prohibitin.
     
 0.599
COX11
Cytochrome c oxidase copper chaperone COX11.
      
 0.596
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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