STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1240 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.860
RAP1GAP2
RAP1 GTPase activating protein 2b.
     
 0.670
ARHGAP9
Rho GTPase activating protein 9.
   
  
 0.669
ARHGAP1
Rho GTPase activating protein 1.
      
 0.668
GRAP2
GRB2 related adaptor protein 2.
   
 0.665
H3AZT3_LATCH
GRB2 related adaptor protein b.
   
 0.665
PDE9A
Phosphodiesterase.
      
 0.659
ZNFX1
Zinc finger NFX1-type containing 1.
      
 0.631
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.627
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.611
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.