Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1240 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.818
ARHGAP9
Rho GTPase activating protein 9.
   
  
 0.696
RAP1GAP2
RAP1 GTPase activating protein 2b.
     
 0.693
ARHGAP1
Rho GTPase activating protein 1.
      
 0.693
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.675
ZNFX1
Zinc finger NFX1-type containing 1.
      
 0.668
PDE9A
Phosphodiesterase.
      
 0.660
CDC42
Cell division cycle 42.
    
 0.623
ITSN2
Intersectin 2.
   
 0.622
DLK1
Delta like non-canonical Notch ligand 1.
    
 0.605
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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