Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM106BTransmembrane protein 106B. (277 aa)    
Predicted Functional Partners:
GRN
Granulin precursor.
      
 0.789
TARDBP
TAR DNA binding protein.
    
 
 0.715
TMEM106C
Transmembrane protein 106C.
    
   0.697
ABCC9
ATP binding cassette subfamily C member 9.
      
 0.659
PYROXD1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
      
 0.655
C9orf72
C9orf72-SMCR8 complex subunit.
      
 0.649
CHMP2B
Charged multivesicular body protein 2B.
    
 
 0.645
EPDR1
Ependymin related 1.
      
 0.641
TMEM41B
Transmembrane protein 41B.
      
 0.628
H3B6R7_LATCH
Ion_trans domain-containing protein.
   
  
 0.616
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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