Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POC1BPOC1 centriolar protein B. (486 aa)    
Predicted Functional Partners:
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.795
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.792
CXXC1
CXXC finger protein 1.
    
 0.740
WDR82
WD repeat domain 82.
   
 0.727
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.712
KANSL2
KAT8 regulatory NSL complex subunit 2.
    
 0.703
PHF20
PHD finger protein 20.
    
 0.689
H3A4E9_LATCH
Uncharacterized protein.
   
 0.679
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
 0.679
WASHC3
WASH complex subunit 3.
    
   0.670
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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