STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL1Cullin 1; Belongs to the cullin family. (776 aa)    
Predicted Functional Partners:
RBX1
Ring-box 1.
    
 0.999
H3A8H2_LATCH
Uncharacterized protein.
   
 0.999
SKP2
S-phase kinase associated protein 2.
    
 0.999
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.999
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.998
UBXN7
UBX domain-containing protein 7.
   
 0.992
FBXL17
F-box and leucine rich repeat protein 17.
    
 0.989
FBXW11
F-box and WD repeat domain containing 11.
   
 0.986
UBE2M
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.986
CCNE1
Cyclin E1; Belongs to the cyclin family.
    
 0.983
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.