SEMA6B protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SEMA6B

Sema domain-containing protein; Belongs to the semaphorin family. (911 aa)

Predicted Functional Partners:

H3AY29_LATCH

0.893

NRP1

0.678

H3A2E1_LATCH

0.641

PLXND1

0.594

PLXNA3-2

0.561

PLXNA1

0.561

PLXNA3

0.561

LOC102347877

0.561

PLXNA2

0.561

MTMR9

0.519

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3A2E1_LATCH	H3AY29_LATCH	ENSLACP00000003812	ENSLACP00000014550	Plexin_cytopl domain-containing protein.	Uncharacterized protein.	0.646
H3A2E1_LATCH	LOC102347877	ENSLACP00000003812	ENSLACP00000012157	Plexin_cytopl domain-containing protein.	Uncharacterized protein.	0.590
H3A2E1_LATCH	NRP1	ENSLACP00000003812	ENSLACP00000023533	Plexin_cytopl domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.873
H3A2E1_LATCH	PLXNA1	ENSLACP00000003812	ENSLACP00000006441	Plexin_cytopl domain-containing protein.	Plexin A1.	0.754
H3A2E1_LATCH	PLXNA2	ENSLACP00000003812	ENSLACP00000021348	Plexin_cytopl domain-containing protein.	Plexin A2.	0.579
H3A2E1_LATCH	PLXNA3	ENSLACP00000003812	ENSLACP00000006959	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.955
H3A2E1_LATCH	PLXNA3-2	ENSLACP00000003812	ENSLACP00000002847	Plexin_cytopl domain-containing protein.	Plexin A3.	0.579
H3A2E1_LATCH	PLXND1	ENSLACP00000003812	ENSLACP00000013783	Plexin_cytopl domain-containing protein.	Plexin D1.	0.574
H3A2E1_LATCH	SEMA6B	ENSLACP00000003812	ENSLACP00000003519	Plexin_cytopl domain-containing protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.641
H3AY29_LATCH	H3A2E1_LATCH	ENSLACP00000014550	ENSLACP00000003812	Uncharacterized protein.	Plexin_cytopl domain-containing protein.	0.646
H3AY29_LATCH	LOC102347877	ENSLACP00000014550	ENSLACP00000012157	Uncharacterized protein.	Uncharacterized protein.	0.512
H3AY29_LATCH	NRP1	ENSLACP00000014550	ENSLACP00000023533	Uncharacterized protein.	Neuropilin; Belongs to the neuropilin family.	0.628
H3AY29_LATCH	PLXNA1	ENSLACP00000014550	ENSLACP00000006441	Uncharacterized protein.	Plexin A1.	0.512
H3AY29_LATCH	PLXNA2	ENSLACP00000014550	ENSLACP00000021348	Uncharacterized protein.	Plexin A2.	0.512
H3AY29_LATCH	PLXNA3	ENSLACP00000014550	ENSLACP00000006959	Uncharacterized protein.	Sema domain-containing protein.	0.512
H3AY29_LATCH	PLXNA3-2	ENSLACP00000014550	ENSLACP00000002847	Uncharacterized protein.	Plexin A3.	0.512
H3AY29_LATCH	PLXND1	ENSLACP00000014550	ENSLACP00000013783	Uncharacterized protein.	Plexin D1.	0.574
H3AY29_LATCH	SEMA6B	ENSLACP00000014550	ENSLACP00000003519	Uncharacterized protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.893
LOC102347877	H3A2E1_LATCH	ENSLACP00000012157	ENSLACP00000003812	Uncharacterized protein.	Plexin_cytopl domain-containing protein.	0.590
LOC102347877	H3AY29_LATCH	ENSLACP00000012157	ENSLACP00000014550	Uncharacterized protein.	Uncharacterized protein.	0.512