Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102366075Uncharacterized protein. (426 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.957
CEP135
Uncharacterized protein.
 
     0.933
H3AJ45_LATCH
Uncharacterized protein.
    
 0.892
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.892
TBC1D31
TBC1 domain family member 31.
   
 0.803
H2ZX87_LATCH
Tcp10_C domain-containing protein.
   
 0.798
CENPJ
Uncharacterized protein.
   
 0.798
PLK4
Polo like kinase 4.
   
 0.792
PLK1
Serine/threonine-protein kinase PLK.
   
 0.777
WRAP73
WD repeat containing, antisense to TP73.
    
 
 0.742
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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