SCAP protein (Latimeria chalumnae) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SCAP

SREBF chaperone. (1283 aa)

Predicted Functional Partners:

SREBF2

0.966

SREBF1

0.966

INSIG2

0.899

INSIG1

0.899

NPC2

0.888

MYCN

0.795

MBTPS1

0.786

HMGCR

0.584

H2ZTK5_LATCH

0.573

SYCP3

0.543

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2ZTK5_LATCH	MBTPS1	ENSLACP00000000726	ENSLACP00000005004	Peptidase_M50 domain-containing protein.	Membrane bound transcription factor peptidase, site 1.	0.702
H2ZTK5_LATCH	MYCN	ENSLACP00000000726	ENSLACP00000009455	Peptidase_M50 domain-containing protein.	MYCN proto-oncogene, bHLH transcription factor.	0.756
H2ZTK5_LATCH	SCAP	ENSLACP00000000726	ENSLACP00000003541	Peptidase_M50 domain-containing protein.	SREBF chaperone.	0.573
H2ZTK5_LATCH	SREBF1	ENSLACP00000000726	ENSLACP00000014939	Peptidase_M50 domain-containing protein.	Sterol regulatory element binding transcription factor 1.	0.799
H2ZTK5_LATCH	SREBF2	ENSLACP00000000726	ENSLACP00000005025	Peptidase_M50 domain-containing protein.	Sterol regulatory element binding transcription factor 2.	0.799
HMGCR	INSIG1	ENSLACP00000010356	ENSLACP00000022490	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.867
HMGCR	INSIG2	ENSLACP00000010356	ENSLACP00000018298	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	0.793
HMGCR	MYCN	ENSLACP00000010356	ENSLACP00000009455	3-hydroxy-3-methylglutaryl coenzyme A reductase.	MYCN proto-oncogene, bHLH transcription factor.	0.529
HMGCR	SCAP	ENSLACP00000010356	ENSLACP00000003541	3-hydroxy-3-methylglutaryl coenzyme A reductase.	SREBF chaperone.	0.584
HMGCR	SREBF1	ENSLACP00000010356	ENSLACP00000014939	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Sterol regulatory element binding transcription factor 1.	0.724
HMGCR	SREBF2	ENSLACP00000010356	ENSLACP00000005025	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Sterol regulatory element binding transcription factor 2.	0.651
INSIG1	HMGCR	ENSLACP00000022490	ENSLACP00000010356	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.867
INSIG1	SCAP	ENSLACP00000022490	ENSLACP00000003541	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	SREBF chaperone.	0.899
INSIG1	SREBF1	ENSLACP00000022490	ENSLACP00000014939	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.632
INSIG1	SREBF2	ENSLACP00000022490	ENSLACP00000005025	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.440
INSIG2	HMGCR	ENSLACP00000018298	ENSLACP00000010356	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.793
INSIG2	SCAP	ENSLACP00000018298	ENSLACP00000003541	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	SREBF chaperone.	0.899
INSIG2	SREBF1	ENSLACP00000018298	ENSLACP00000014939	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	Sterol regulatory element binding transcription factor 1.	0.440
INSIG2	SREBF2	ENSLACP00000018298	ENSLACP00000005025	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.	Sterol regulatory element binding transcription factor 2.	0.440
MBTPS1	H2ZTK5_LATCH	ENSLACP00000005004	ENSLACP00000000726	Membrane bound transcription factor peptidase, site 1.	Peptidase_M50 domain-containing protein.	0.702