Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H3A1M4_LATCHUncharacterized protein. (457 aa)    
Predicted Functional Partners:
LOC102362765
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.949
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
   
 
 0.945
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
   
 
 0.940
LOC102365730
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.934
H3A831_LATCH
Aldehyde oxidase 5.
   
 
 0.925
AOX1
FAD-binding PCMH-type domain-containing protein.
   
 
 0.925
CYP19A1
Cytochrome P450 family 19 subfamily A member 1.
   
 0.925
SRD5A3
Steroid 5 alpha-reductase 3.
     
 0.924
CYP26B1
Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 0.916
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.916
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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