Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMBPAlpha-1-microglobulin/bikunin precursor. (350 aa)    
Predicted Functional Partners:
AHSG
Alpha 2-HS glycoprotein.
   
  
 0.961
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.957
APOH
Apolipoprotein H.
   
  
 0.933
LOC102358196
Uncharacterized protein.
   
 
 0.928
FGA
Fibrinogen alpha chain.
   
  
 0.927
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 
 0.894
FGB
Fibrinogen beta chain.
   
  
 0.890
LOC102345227
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.873
LOC102365063
Apolipoprotein A-IV b, tandem duplicate 2.
   
 
 0.869
AGT
SERPIN domain-containing protein; Belongs to the serpin family.
   
 
 0.856
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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