Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (295 aa)    
Predicted Functional Partners:
PHAX
Phosphorylated adaptor for RNA export.
    
   0.953
RAB29
RAB29, member RAS oncogene family.
 
    
 0.906
PM20D1
Peptidase M20 domain containing 1.
      
 0.792
HSPG2
Heparan sulfate proteoglycan 2.
      
 0.641
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
      
 0.615
ZNF593
Zinc finger protein 593.
      
 0.613
WDHD1
WD repeat and HMG-box DNA binding protein 1.
      
 0.613
SLC45A3
Solute carrier family 45 member 3.
      
 0.606
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
   0.606
DDRGK1
DDRGK domain containing 1.
      
 0.596
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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