Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PIGNPhosphatidylinositol glycan anchor biosynthesis class N. (811 aa)    
Predicted Functional Partners:
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 0.992
PIGB
Mannosyltransferase.
     
 0.989
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
      
 0.931
PIGH
Phosphatidylinositol glycan anchor biosynthesis class H.
      
 0.925
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
  
 0.913
PIGM
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
      
 0.872
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
      
 0.835
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
   
 
 0.816
LEMD3
LEM domain containing 3.
      
 0.812
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
    
 0.793
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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