Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAMD12Sterile alpha motif domain containing 12. (180 aa)    
Predicted Functional Partners:
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
    
 0.892
CNKSR3
Uncharacterized protein.
    
 0.829
IPCEF1
PH domain-containing protein.
    
 0.829
CNKSR1
Connector enhancer of kinase suppressor of Ras 1.
    
 0.708
KSR2-2
Si:ch73-263f13.1.
    
 0.679
KSR2
Kinase suppressor of ras 2.
    
 0.679
KSR1
Kinase suppressor of ras 1.
    
 0.679
H3AX34_LATCH
Eph LBD domain-containing protein.
    
 0.662
ARRDC4
Arrestin domain containing 4.
      
 0.658
MYO1D
Myosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.658
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.