Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CALHM1Calcium homeostasis modulator 1. (341 aa)    
Predicted Functional Partners:
TRPM5
Transient receptor potential cation channel subfamily M member 5.
      
 0.769
PDE1A
Phosphodiesterase.
      
 0.722
GNAT3
G protein subunit alpha transducin 3.
      
 0.664
OTOP1
Otopetrin 1.
   
  
 0.648
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
      
 0.645
ANO6
Anoctamin.
      
 0.641
CALHM3
Calcium homeostasis modulator 3.
     
 0.640
LOC102354918
Uncharacterized protein.
     
 0.640
TSPO
Translocator protein.
      
 0.634
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.634
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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