Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPZCarboxypeptidase Z. (611 aa)    
Predicted Functional Partners:
AFF1
AF4/FMR2 family member 1.
    
 
 0.706
AGMO
Uncharacterized protein.
      
 0.662
SPCS1
Signal peptidase complex subunit 1.
      
 0.634
GPR78
G protein-coupled receptor 78b.
   
  
 0.629
CRPPA
CDP-L-ribitol pyrophosphorylase A.
      
 0.591
EDA
Ectodysplasin A; Belongs to the tumor necrosis factor family.
      
 0.587
GAK
J domain-containing protein.
     
  0.570
MFRP
Membrane frizzled-related protein.
      
 0.570
SORCS2
Sortilin related VPS10 domain containing receptor 2.
     
 0.551
LUC7L3
LUC7 like 3 pre-mRNA splicing factor.
      
 0.545
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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