Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102356003SH2 domain-containing protein. (170 aa)    
Predicted Functional Partners:
IFNAR1
Uncharacterized protein.
   
 0.954
LOC102367350
Fibronectin type-III domain-containing protein.
   
 0.936
STAT3
Signal transducer and activator of transcription.
   
 0.936
IL6ST
Interleukin 6 signal transducer.
    
 0.925
SOCS1
Suppressor of cytokine signaling 1a.
    
 0.920
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
 
      0.900
H2ZZ29_LATCH
Uncharacterized protein.
   
 0.866
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.862
LOC102352712
Protein tyrosine phosphatase non-receptor type 11b.
   
 0.862
IL10RB
Uncharacterized protein.
   
 0.849
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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