Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.735
LOC102358409
Uncharacterized protein.
   
 0.699
FGG
Fibrinogen gamma chain.
   
 0.687
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
  
0.681
PELI2
Pellino E3 ubiquitin protein ligase family member 2.
      
 0.658
AHSG
Alpha 2-HS glycoprotein.
   
 
 0.656
KNG1
Uncharacterized protein.
   
 
 0.632
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
  
 
0.601
AREG
Amphiregulin.
     
 0.593
LMAN1
Lectin, mannose binding 1.
    
 0.593
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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