STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2HGDHD-2-hydroxyglutarate dehydrogenase. (564 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
    
 0.929
DMAP1
DNA methyltransferase 1 associated protein 1.
   
 0.914
TRA2B
Transformer 2 beta homolog.
   
 
 0.894
YEATS4
YEATS domain containing 4.
   
 0.886
SLITRK3
SLIT and NTRK like family member 3.
      
 0.876
MORF4L1
Mortality factor 4 like 1.
   
 0.871
EPC2
Enhancer of polycomb homolog.
   
 0.785
EPC1
Enhancer of polycomb homolog.
   
 0.785
TRRAP
Transformation/transcription domain-associated protein.
   
 0.764
LOC102351641
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.764
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.