Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
D2HGDHD-2-hydroxyglutarate dehydrogenase. (564 aa)    
Predicted Functional Partners:
SLITRK3
SLIT and NTRK like family member 3.
      
 0.869
L2HGDH
L-2-hydroxyglutarate dehydrogenase.
      
 0.867
TRA2B
Transformer 2 beta homolog.
   
 
 0.864
YEATS4
YEATS domain containing 4.
   
 0.860
DMAP1
DNA methyltransferase 1 associated protein 1.
   
 0.860
MORF4L1
Mortality factor 4 like 1.
   
 0.857
MEAF6
MYST/Esa1 associated factor 6.
    
 0.842
IDH2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
      
 0.800
PHLDB1
Pleckstrin homology like domain family B member 1.
      
 0.790
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.748
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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