Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (431 aa)    
Predicted Functional Partners:
GGCX
Gamma-glutamyl carboxylase.
    
 0.800
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
0.794
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.783
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 0.765
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
  0.710
F3
Coagulation factor III, tissue factor.
    
 0.661
SERPINA10
Serpin family A member 10; Belongs to the serpin family.
   
 0.646
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
   
 0.611
LOC102358369
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  0.609
LOC102358409
Uncharacterized protein.
   
  0.574
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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