Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL17REInterleukin 17 receptor E. (490 aa)    
Predicted Functional Partners:
IL17C
Uncharacterized protein.
    
 0.969
LOC102362454
Uncharacterized protein.
    
 0.969
IL17RD
Interleukin 17 receptor D.
    
 0.862
IL17RB
SEFIR domain-containing protein.
      
0.755
H3B9K7_LATCH
SEFIR domain-containing protein.
    
 0.726
LOC102356424
Nuclear factor, interleukin 3 regulated, member 6.
      
 0.658
PURA
Purine rich element binding protein A.
      
 0.654
VGLL4
Vestigial like family member 4.
      
 0.641
MKRN2
Makorin ring finger protein 2.
      
 0.641
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
  
 0.616
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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