Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OTOP1Otopetrin 1. (584 aa)    
Predicted Functional Partners:
H3AFJ9_LATCH
SPARC-like 2.
      
 0.808
H3AU65_LATCH
Phospholipase A(2).
      
 0.796
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
      
 0.703
OTOL1
Otolin 1.
      
 0.690
CALHM1
Calcium homeostasis modulator 1.
   
  
 0.648
TECTA
Tectorin alpha.
      
 0.641
LOC102347946
Transferrin-like domain-containing protein.
      
 0.641
LOC102353852
Uncharacterized protein.
      
 0.633
TMEM128
Transmembrane protein 128.
      
 0.599
RFTN2
Raftlin family member 2.
      
 0.593
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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