STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1059 aa)    
Predicted Functional Partners:
SYPL1
Synaptophysin like 1.
      
 0.749
ELOVL7
Elongation of very long chain fatty acids protein.
      
 0.670
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.662
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.596
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
      
 0.579
PLXND1
Plexin D1.
    
 0.547
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.540
H3AY29_LATCH
Uncharacterized protein.
 
    
 0.516
H3A2E1_LATCH
Plexin_cytopl domain-containing protein.
    
 0.511
TMEM38B
Transmembrane protein 38B.
      
 0.461
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.