Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1059 aa)    
Predicted Functional Partners:
SYPL1
Synaptophysin like 1.
      
 0.799
ELOVL7
Elongation of very long chain fatty acids protein.
      
 0.726
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.667
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
      
 0.659
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.651
TMEM38B
Transmembrane protein 38B.
      
 0.615
SAP18
Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins.
      
 0.565
PLXND1
Plexin D1.
    
 0.561
H3A2E1_LATCH
Plexin_cytopl domain-containing protein.
    
 0.539
H3AY29_LATCH
Uncharacterized protein.
 
    
 0.517
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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