STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPENSpen family transcriptional repressor. (3610 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 
 0.917
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 
 0.674
PDE7A
Phosphodiesterase.
     
 0.657
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
  
 0.607
WTAP
WT1 associated protein.
    
 
 0.576
SYT11
Synaptotagmin 11.
      
 0.575
ILF3
Interleukin enhancer binding factor 3.
      
 0.572
MYCBP
MYC binding protein.
      
 0.571
MSX2
Msh homeobox 2.
    
 
 0.567
MYCBP2
MYC binding protein 2.
   
  
 0.548
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.