Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRATD2LRAT domain containing 2. (273 aa)    
Predicted Functional Partners:
UROD
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
    
   0.938
VWA5B2
Von Willebrand factor A domain containing 5B2.
      
 0.677
ECPAS
Ecm29 proteasome adaptor and scaffold.
      
 0.641
VWA8
Von Willebrand factor A domain containing 8.
      
 0.605
TRMT61B
tRNA methyltransferase 61B.
      
 0.604
TICRR
TOPBP1 interacting checkpoint and replication regulator.
      
 0.594
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.
      
 0.588
FAM81A
Family with sequence similarity 81 member A.
      
 0.586
STYX
Serine/threonine/tyrosine interacting protein.
      
 0.584
ENDOV
Endonuclease V.
    
   0.558
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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