Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CIDEACell death inducing DFFA like effector a. (225 aa)    
Predicted Functional Partners:
DFFB
DNA fragmentation factor subunit beta.
    
 0.894
TMEM26
Transmembrane protein 26.
      
 0.744
PRDM16-2
Si:ch211-263k4.2.
     
 0.715
PRDM16
PR/SET domain 16.
     
 0.715
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
 0.707
SPRY1
Sprouty RTK signaling antagonist 1.
      
 0.702
CIDEC
Cell death inducing DFFA like effector c.
    
  0.690
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
   
  
 0.678
UCP1
Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.661
DIO2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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