Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A214_LATCHUncharacterized protein. (559 aa)    
Predicted Functional Partners:
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.849
CXXC1
CXXC finger protein 1.
   
 0.848
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.848
WDR5B
WD repeat domain 5B.
   
 0.769
NEU1
Neuraminidase 1.
  
 0.690
MSL3
MSL complex subunit 3.
    
 
 0.657
H3A4E9_LATCH
Uncharacterized protein.
   
 0.625
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
 0.625
MARS2
Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.621
IMMT
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
   0.618
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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