Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A246_LATCHUncharacterized protein. (920 aa)    
Predicted Functional Partners:
PTGES3
Prostaglandin E synthase 3.
    
 0.825
ARNT2
Uncharacterized protein.
   
 0.817
ARNT2-2
Aryl-hydrocarbon receptor nuclear translocator 2.
   
 0.817
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
 0.817
LOC102357218
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.737
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
    
 0.737
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
    
 0.737
ESR2
Estrogen receptor 2.
   
 
 0.666
CTNNB1
Catenin beta 1.
    
 
 0.661
RB1
Uncharacterized protein.
    
   0.648
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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