Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNYCyclin Y; Belongs to the cyclin family. (257 aa)    
Predicted Functional Partners:
CDK14
Cyclin dependent kinase 14; Belongs to the protein kinase superfamily.
   
 
 0.883
CDK17
Cyclin dependent kinase 17.
   
 
 0.667
LOC102346156
Protein kinase domain-containing protein.
   
 
 0.667
CDK15
Cyclin dependent kinase 15; Belongs to the protein kinase superfamily.
   
 
 0.631
CDK18
Cyclin dependent kinase 18.
   
 
 0.593
MANF
Mesencephalic astrocyte derived neurotrophic factor.
      
 0.564
PITHD1
PITH domain containing 1.
 
      0.498
CDK5
Cyclin dependent kinase 5.
      
 0.477
PIBF1
Progesterone immunomodulatory binding factor 1.
      
 0.453
CCNC
Cyclin C; Belongs to the cyclin family.
      
 0.448
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]