Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASPHAspartate beta-hydroxylase. (435 aa)    
Predicted Functional Partners:
H3AEH3_LATCH
Asp-B-Hydro_N domain-containing protein.
 
   
  0.989
CASQ1
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 
 0.952
CASQ2
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 
 0.952
RYR3
Uncharacterized protein.
   
 
 0.909
RYR2
Ryanodine receptor 2b (cardiac).
   
 
 0.909
RYR1
Ryanodine receptor 1.
   
 
 0.909
PSPH
Phosphoserine phosphatase.
      
 0.795
MACF1
Microtubule actin crosslinking factor 1.
      
 0.650
FKBP1A
Peptidylprolyl isomerase.
     
 0.641
FKBP1B
Peptidylprolyl isomerase.
     
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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