Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LY75Uncharacterized protein. (1730 aa)    
Predicted Functional Partners:
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.806
HIVEP3
Human immunodeficiency virus type I enhancer binding protein 3.
   
 0.731
IK
IK cytokine.
      
 0.725
HIVEP2
Human immunodeficiency virus type I enhancer binding protein 2.
   
 0.671
MTRF1L
Mitochondrial translational release factor 1 like.
      
 0.635
TNFAIP3
TNF alpha induced protein 3.
      
 0.605
NANOS2
Nanos-type domain-containing protein; Belongs to the nanos family.
      
 0.589
LOC102362196
Ig-like domain-containing protein.
      
 0.565
TSPO
Translocator protein.
      
 0.559
LOC102367579
Translocator protein 2.
      
 0.551
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (52%) [HD]