H3A2B2_LATCH protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

H3A2B2_LATCH

Uncharacterized protein. (3021 aa)

Predicted Functional Partners:

LOC102363517

0.950

H2ZTK1_LATCH

0.939

LOC102356522

0.933

H3AEZ5_LATCH

0.921

H2ZTL3_LATCH

0.890

DCTN1

0.745

PAFAH1B1

0.731

DNAI2

0.729

DCTN2

0.708

DYNLL1

0.684

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCTN1	DCTN2	ENSLACP00000008350	ENSLACP00000020983	Dynactin 1a.	Dynactin subunit 2.	0.999
DCTN1	DNAI2	ENSLACP00000008350	ENSLACP00000020076	Dynactin 1a.	Dynein axonemal intermediate chain 2.	0.569
DCTN1	DYNLL1	ENSLACP00000008350	ENSLACP00000020737	Dynactin 1a.	Dynein light chain.	0.960
DCTN1	H2ZTK1_LATCH	ENSLACP00000008350	ENSLACP00000000722	Dynactin 1a.	Uncharacterized protein.	0.745
DCTN1	H2ZTL3_LATCH	ENSLACP00000008350	ENSLACP00000000734	Dynactin 1a.	Dynein_C domain-containing protein.	0.423
DCTN1	H3A2B2_LATCH	ENSLACP00000008350	ENSLACP00000003783	Dynactin 1a.	Uncharacterized protein.	0.745
DCTN1	H3AEZ5_LATCH	ENSLACP00000008350	ENSLACP00000008216	Dynactin 1a.	Uncharacterized protein.	0.745
DCTN1	LOC102356522	ENSLACP00000008350	ENSLACP00000013253	Dynactin 1a.	Uncharacterized protein.	0.423
DCTN1	LOC102363517	ENSLACP00000008350	ENSLACP00000009626	Dynactin 1a.	Uncharacterized protein.	0.423
DCTN1	PAFAH1B1	ENSLACP00000008350	ENSLACP00000020703	Dynactin 1a.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	0.978
DCTN2	DCTN1	ENSLACP00000020983	ENSLACP00000008350	Dynactin subunit 2.	Dynactin 1a.	0.999
DCTN2	DNAI2	ENSLACP00000020983	ENSLACP00000020076	Dynactin subunit 2.	Dynein axonemal intermediate chain 2.	0.700
DCTN2	DYNLL1	ENSLACP00000020983	ENSLACP00000020737	Dynactin subunit 2.	Dynein light chain.	0.821
DCTN2	H2ZTK1_LATCH	ENSLACP00000020983	ENSLACP00000000722	Dynactin subunit 2.	Uncharacterized protein.	0.708
DCTN2	H2ZTL3_LATCH	ENSLACP00000020983	ENSLACP00000000734	Dynactin subunit 2.	Dynein_C domain-containing protein.	0.564
DCTN2	H3A2B2_LATCH	ENSLACP00000020983	ENSLACP00000003783	Dynactin subunit 2.	Uncharacterized protein.	0.708
DCTN2	H3AEZ5_LATCH	ENSLACP00000020983	ENSLACP00000008216	Dynactin subunit 2.	Uncharacterized protein.	0.708
DCTN2	LOC102356522	ENSLACP00000020983	ENSLACP00000013253	Dynactin subunit 2.	Uncharacterized protein.	0.564
DCTN2	LOC102363517	ENSLACP00000020983	ENSLACP00000009626	Dynactin subunit 2.	Uncharacterized protein.	0.564
DCTN2	PAFAH1B1	ENSLACP00000020983	ENSLACP00000020703	Dynactin subunit 2.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.	0.950