Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCM1Glial cells missing transcription factor 1. (443 aa)    
Predicted Functional Partners:
CRYAB
Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.
      
 0.793
S100B
S100 calcium binding protein B; Belongs to the S-100 family.
      
 0.791
HOPX
Homeobox domain-containing protein.
    
 
 0.736
HTRA4
HtrA serine peptidase 4.
    
 
 0.725
HTRA1
HtrA serine peptidase 1.
    
 
 0.725
FBXW2
F-box and WD repeat domain containing 2.
   
 
 0.694
ICK
Intestinal cell kinase.
      
 0.687
CREBBP
CREB binding protein.
    
   0.678
FGFR3
Fibroblast growth factor receptor.
    
 
 0.676
CRK
CRK proto-oncogene, adaptor protein.
      
 0.654
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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