Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
UBE2L6UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (144 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.988
RNF31
Uncharacterized protein.
   
 0.985
WWP1
E3 ubiquitin-protein ligase.
    
 0.982
RPS27A
Ribosomal protein S27a.
   
 0.981
RBX1
Ring-box 1.
   
 0.980
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.980
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1.
    
 0.979
WWP2
E3 ubiquitin-protein ligase.
    
 0.976
ITCH
E3 ubiquitin-protein ligase.
    
 0.976
UBE3C
Ubiquitin protein ligase E3C.
    
 0.973
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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