H3A2C7_LATCH protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

H3A2C7_LATCH

Uncharacterized protein. (683 aa)

Predicted Functional Partners:

PHF20L1

0.903

UBXN4

0.898

H3B480_LATCH

0.891

SMARCB1

0.670

SMARCE1

0.652

CDK2AP2

0.615

RBBP7

0.609

LOC102347269

0.609

RBBP4

0.609

HDAC8

0.602

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK2AP2	H3A2C7_LATCH	ENSLACP00000005165	ENSLACP00000003798	Cyclin dependent kinase 2 associated protein 2.	Uncharacterized protein.	0.615
CDK2AP2	H3B480_LATCH	ENSLACP00000005165	ENSLACP00000016701	Cyclin dependent kinase 2 associated protein 2.	Uncharacterized protein.	0.798
CDK2AP2	HDAC8	ENSLACP00000005165	ENSLACP00000012893	Cyclin dependent kinase 2 associated protein 2.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.668
CDK2AP2	LOC102347269	ENSLACP00000005165	ENSLACP00000014675	Cyclin dependent kinase 2 associated protein 2.	Retinoblastoma binding protein 4, like.	0.645
CDK2AP2	RBBP4	ENSLACP00000005165	ENSLACP00000018242	Cyclin dependent kinase 2 associated protein 2.	RB binding protein 4, chromatin remodeling factor.	0.645
CDK2AP2	RBBP7	ENSLACP00000005165	ENSLACP00000014030	Cyclin dependent kinase 2 associated protein 2.	WD_REPEATS_REGION domain-containing protein.	0.645
H3A2C7_LATCH	CDK2AP2	ENSLACP00000003798	ENSLACP00000005165	Uncharacterized protein.	Cyclin dependent kinase 2 associated protein 2.	0.615
H3A2C7_LATCH	H3B480_LATCH	ENSLACP00000003798	ENSLACP00000016701	Uncharacterized protein.	Uncharacterized protein.	0.891
H3A2C7_LATCH	HDAC8	ENSLACP00000003798	ENSLACP00000012893	Uncharacterized protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.602
H3A2C7_LATCH	LOC102347269	ENSLACP00000003798	ENSLACP00000014675	Uncharacterized protein.	Retinoblastoma binding protein 4, like.	0.609
H3A2C7_LATCH	PHF20L1	ENSLACP00000003798	ENSLACP00000005831	Uncharacterized protein.	PHD finger protein 20 like 1.	0.903
H3A2C7_LATCH	RBBP4	ENSLACP00000003798	ENSLACP00000018242	Uncharacterized protein.	RB binding protein 4, chromatin remodeling factor.	0.609
H3A2C7_LATCH	RBBP7	ENSLACP00000003798	ENSLACP00000014030	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.609
H3A2C7_LATCH	SMARCB1	ENSLACP00000003798	ENSLACP00000010836	Uncharacterized protein.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.670
H3A2C7_LATCH	SMARCE1	ENSLACP00000003798	ENSLACP00000015784	Uncharacterized protein.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.652
H3A2C7_LATCH	UBXN4	ENSLACP00000003798	ENSLACP00000009109	Uncharacterized protein.	UBX domain protein 4.	0.898
H3B480_LATCH	CDK2AP2	ENSLACP00000016701	ENSLACP00000005165	Uncharacterized protein.	Cyclin dependent kinase 2 associated protein 2.	0.798
H3B480_LATCH	H3A2C7_LATCH	ENSLACP00000016701	ENSLACP00000003798	Uncharacterized protein.	Uncharacterized protein.	0.891
H3B480_LATCH	HDAC8	ENSLACP00000016701	ENSLACP00000012893	Uncharacterized protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.637
H3B480_LATCH	LOC102347269	ENSLACP00000016701	ENSLACP00000014675	Uncharacterized protein.	Retinoblastoma binding protein 4, like.	0.515